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cancer research reagents

Zearalenone

MSDS Sample CoA
 
Source: Giberella zeae
SynonymsFES,
Compound F-2,
Toxin F2.

IUPAC name: (3S,11E)-14,16-dihydroxy-3-methyl-3,4,5,6,9,10-hexahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione

Description: Zearalenone is a naturally occurring estrogen, a mycotoxin from resorcylic acid lactone group.  It is named after the species name of the fungus that produces it.
CAS number: 17924-92-4
Merck index: 13,10169
Molecular weight: 318.4
Structure:

Molecular Formula: C18H22O5
Canonical SMILES CC1CCCC(=O)CCCC=CC2=CC(=CC(=C2C(=O)O1)O)O
Solubility
information:
Solubility of Zearalenone in water is about 0.002g/100ml. Zearalenone  is slightly soluble in hexane and progressively more  in benzene, acetonitrile, dichloromethane, methanol, acetone.
Specifications 
Appearance: White powder
Purity: At least 98% by TLC, HPLC
λmax:(in methanol) 236,274,316.
Melting point:159C - 163C
Solubility:Clear colourless solution at 5mg/ml Methanol
Storage:-20°C.
Applications:The resorcylic acid lactones have estrogenic activity.
Zearalenone and its derivates were used as veterinary anabolic or estrogen substitutes.
Classification: A resorcylic acid lactone
Mycotoxin
Related products: Deoxynivalenol (Vomitoxin), Brefeldin
Warnings: TOXIC.
 

For Research use only. Not for Human or Drug use

Animal ingredient freeZearalenone by Fermentek is not produced from or contains any ingredients from animal origin.

No genetically modified organisms are used.

Publications 
 Songsermsakul P, Sontag G, Cichna-Markl M, Zentek J, Razzazi-Fazeli E.
Determination of zearalenone and its metabolites in urine, plasma and faeces of horses by HPLC-APCI-MS.
J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Jul 7
 Ding X, Lichti K, Staudinger JL.
The mycoestrogen zearalenone induces CYP3A through activation of the pregnane X receptor
.
Toxicol Sci. 2006 Jun;91(2):448-55
AVAILABLE
Standard solutions

 Zearalenone solution





Zearalenone on Wikipedia


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