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Source: | Giberella zeae |
| Synonyms | FES, Compound F-2, Toxin F2.
IUPAC name: (3S,11E)-14,16-dihydroxy-3-methyl-3,4,5,6,9,10-hexahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione |
| Description: | Zearalenone is a naturally occurring estrogen, a mycotoxin from resorcylic acid lactone group.
It is named after the species name of the fungus that
produces it. |
| CAS number: | 17924-92-4 |
| Merck index: | 13,10169 |
| Molecular weight: | 318.4 |
| Structure: |
 |
| Molecular Formula: | C18H22O5 |
Solubility
information: | Solubility of Zearalenone in water is about 0.002g/100ml. Zearalenone is slightly soluble in hexane and progressively more in benzene, acetonitrile, dichloromethane, methanol, acetone. |
| Specifications | |
| Appearance: | White powder |
| Purity: | At least 98% by TLC, HPLC |
| λmax: | (in methanol) 236,274,316. |
| Melting point: | 159°C - 163°C |
| Solubility: | Clear colourless solution at 5mg/ml Methanol |
| Storage: | -20°C. |
| Applications: | The resorcylic acid lactones have estrogenic activity.
Zearalenone and its derivates were used as veterinary anabolic or estrogen substitutes. |
| Classification: |
A resorcylic acid lactone
Mycotoxin |
| Related products: |
Deoxynivalenol (Vomitoxin), Brefeldin |
| Warnings: |
 TOXIC. |
| | For Research use only. Not for Human or Drug use
GMP/API grade available on request
7AAD by Fermentek is not produced from or contains any ingredients from animal origin.
No genetically modified organisms are used. |
| Publications | |
| | Songsermsakul P, Sontag G, Cichna-Markl M, Zentek J, Razzazi-Fazeli E.
Determination of zearalenone and its metabolites in urine, plasma and faeces of horses by HPLC-APCI-MS.
J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Jul 7 |
| | Ding X, Lichti K, Staudinger JL.
The mycoestrogen zearalenone induces CYP3A through activation of the pregnane X receptor.
Toxicol Sci. 2006 Jun;91(2):448-55 |
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