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cancer research reagents

Tentoxin

MSDSSample CoA
 
Source: Alternaria alternata
Synonyms Cycloleucyl-N-methylalanylglycyl-N-methyl dehydrophenylalanine
IUPAC Name: (3S,6S,12Z)-12-benzylidene-1,6,7-trimethyl-3-(2-methylpropyl)-1,4,7,10-tetrazacyclododecane-2,5,8,11-tetrone
Description: Cyclic peptide from fungus Alternaria
CAS number: 28540-82-1
Merck index: NA
Molecular weight: 414.5
Structure:

The molecular structure of Tentoxin. Free to copy

 

Molecular Formula: C22H30N4O4
Canonical SMILES CC1C(=O)NC(C(=O)N(C(=CC2=CC=CC=C2)C(=O)NCC(=O)N1C)C)CC(C)C
Solubility
information:

Tentoxin is soluble in Ethanol (10 mg/ml), with heat as needed
Water, Dichloromethane, DMSO

Specifications 
Appearance: Off white to yellow powder
Purity: At least 98% by TLC, HPLC; current lot 98.5% by HPLC
λmax:205, 285 nm
Melting point175-180 °C
SolubilityClear colorless solution at 10mg of Tentoxin in 1 ml of DMSO
10mg of Tentoxin in 1 ml of methanol
Storage+4°C.
ApplicationsTentoxin was used to eliminate polyphenol oxidase (PPO) activity from seedlings of higher plants
ClassificationCyclic peptide
chloroplast ATP synthaseinhibitor
Related products 
Warnings 
 For Research use only. Not for Human or Drug use
GMP/API grade available on request
Tentoxin by Fermentek is not produced from or contains any ingredients from animal origin.
No genetically modified organisms are used.
Publications 
 He F, Samra HS, Johnson EA, Degner NR, McCarty RE, Richter ML.
Tentoxin: C-Terminal mutations in the chloroplast ATP synthase gamma subunit impair ATP synthesis and stimulate ATP hydrolysis.
Biochemistry. 2008 Jan 15;47(2):836-44.
 Halloin JM, De Zoeten GA, Walker JC.
The effects of tentoxin on chlorophyll synthesis and plastid structure in cucumber and cabbage.
Plant Physiol. 1970 Mar;45(3):310-4.


tentoxin is formed by alternaria alternata

Alternaria alternata.

 



Tentoxin on Wikipedia


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