| Source: | Fusarium tricinctum |
| Synonyms | Fusariotoxin T2
T2 TOXIN
MYCOTOXIN T2
8-(3-Methylbutyryloxy)diacetoxyscirpenol
Trichothec-9-ene-3.alpha.,8.alpha.,15-tetrol, 12,13-epoxy-,
4,15-diacetate 8-isovalerate |
| Description: | T2 Toxin: A trichothecene group mycotoxin, of the most important Fusarium toxins. |
| CAS number: | 21259-20-1 |
| Merck index: | |
| Molecular weight: | 466.6 |
| Structure: |
 |
| Molecular Formula: | C24H34O9 |
| Canonical SMILES |
CC1=CC2C(CC1OC(=O)CC(C)C)(C3(C(C(C(C34CO4)O2)O)OC(=O)C)C)COC(=O)C |
Solubility
information: | Dichloromethane, DMSO, Ethanol, Ethyl Acetate. Slightly soluble in petroleum ether; very slightly soluble in water. |
| Specifications |
|
| Appearance: | White crystalline solid. |
| Purity: | At least 98% by TLC, HPLC |
| λmax: | |
| Melting point | 151°C-152°C |
| Solubility | Clear colorless solution at 5 mg/ml of Dichloromethane. |
| Storage | -20°C |
| Applications | T-2 toxin has been recently reported to be used to increase blood-brain barrier permeability in rats. |
| Warnings |
 Very
toxic - T+. Highly irritating
to skin and mucous nembranes. Direct contact may cause extensive
inflammation and tissue necrosis. May be lethal. |
| Classification | Trichothecene
Mycotoxin |
| Related products | T2 toxin ,
Vomitoxin (deoxynivalenol) ,
Deacetoxyscirpenol (DAS) |
| | For Research use only. Not for Human or Drug use
GMP/API grade available on request
No genetically modified organisms are used. |
| Publications |
|
| | Muller G, Kielstein P, Rosner H, Berndt A, Heller M, Kohler H.
Studies on the influence of combined administration of ochratoxin A, fumonisin B1, deoxynivalenol and T2 toxin on immune and defence reactions in weaner pigs.
Mycoses. 1999;42(7-8):485-93 |
| | Lafarge-Frayssinet C, Chakor K, Lafont P, Frayssinet C.
Transplacental transfer of T2-toxin: pathological effect.
J Environ Pathol Toxicol Oncol. 1990 Jan-Apr;10(1-2):64-8 |
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