|
Source: |
Streptomyces achromogenes
|
| Synonyms |
Streptozocin, Streptozotocin, Zanosar
D-Glucopyranose, 2-deoxy-2-(((methylnitrosoamino)carbonyl)amino)-
D-Glucose, 2-deoxy-2-(((methylnitrosoamino)carbonyl)amino)- |
| Description: |
Streptozotocin is a natural glucosamine nitrosourea
antibiotic.
|
| CAS number: | 18883-66-4 |
| Merck index: |
|
| Molecular weight: |
265.2
|
| Structure: |
 |
| Molecular Formula: | C8H15N3O7 |
| Canonical SMILES: |
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Solubility
information: | Water soluble 5 g/L at 25oC |
| Specifications | |
| Appearance: |
White to pale yellowish solid |
| Purity: |
|
| λmax: | |
| Melting point: |
120oC-124oC |
| Solubility: |
|
| Storage: |
|
| Applications: |
Streptozocin is used to induce Type 1 diabetes for medical
research.
Streptozotocin is used in medicine since 1982 as a drug against certain
cancers of the Langerhans Islets. It is cytotoxic to neuroendocrine tumor cell
lines that express the GLUT2 glucose transporter. |
| Related products: | |
| Classification: |
aminoglycoside antibiotic |
| Warnings: |
 toxic |
| | For Research use only. Not for Human or Drug use
|
| Publications | |
| | Streptozotocin and its production.
Bergy M. E. et al., US Patent 3,027,300
1958 |
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