Appl Environ Microbiol. 2005 Dec;71(12):8963-5.
An aflatoxin biosynthesis cluster gene encodes a novel
oxidase required for conversion of versicolorin a to
sterigmatocystin.
Ehrlich KC, Montalbano B, Bou SM, Bhatnagar D.
SRRC/ARS/USDA, 1100 R. E. Lee Blvd., P.O. Box 19687, New
Orleans, LA 70179, USA.
ehrlich@srrc.ars.usda.gov
Disruption of the aflatoxin biosynthesis cluster gene aflY
(hypA) gave Aspergillus parasiticus transformants that
accumulated versicolorin A. This gene is predicted to encode the
Baeyer-Villiger oxidase necessary for formation of the xanthone
ring of the aflatoxin precursor demethylsterigmatocystin.
PMID: 16332900 |
