Fabre S, Prudhomme M, Rapp M.Protein kinase C inhibitors;
structure-activity relationships in K252c-related compounds.
Bioorg Med Chem. 1993 Sep;1(3):193-6
Université Blaise Pascal, Laboratoire de Chimie Organique
Biologique, URA 485, Aubière, France.
K252c-related compounds were synthesized with different
framework flexibilities and different functions (imide, amide
and amide-alcohol) on the non-indolic heterocycle. The
inhibitory activities towards protein kinase C and protein
kinase A are compared.
PMID: 8081852 |
