| Source: |
Penicillium palitans |
| Synonyms | Tremortin A |
| Description: | Penitrem A: a
tremorgenic indole alkaloid that potently inhibits smooth muscle
high-conductance calcium-activated potassium channels. |
| CAS number: | 12627-35-9 |
| Merck index: | |
| Molecular weight: | 634.2 |
| Structure: | 
 |
| Molecular Formula: | C37H44ClNO6 |
| Canonical SMILES: | CC(=C)C1C(C2C3(O2)C(O1)CCC4(C3(CCC5C4(C6=C7C5OC(C8CC9C8(C1=C7C(=CC(= C1CC9=C)Cl)N6)O)(C)C)C)O)C)O |
Solubility
information: | Acetone,
Methanol, and DMSO. |
| Specifications: | |
| Appearance: | White powder |
| Purity: | At least 95% by TLC, HPLC |
| λmax: | |
| Melting point: | (decomposition) 224°C-230°C |
| Solubility: | Clear colorless solution at
10mg/ml of Methanol |
| Storage: | -20°C. Protect from light. |
| Applications | |
| Warnings | NEUROTOXIN |
| Classification | indole alkaloid
mycotoxin |
| Related products | |
| |
For Research use only. Not
for Human or Drug use.
GMP/API grade may be available on request
 Penitrem A by
Fermentek is not produced from or contains any ingredients from animal
origin.
No genetically modified organisms are used. |
| Publications | |
| | Tor ER, Puschner B, Filigenzi MS,
Tiwary AK, Poppenga RH.
LC-MS/MS screen for penitrem A and roquefortine C in serum and urine samples.
Anal Chem. 2006 Jul 1;78(13):4624-9. |
| | Rundberget T, Skaar I, O'Brien O,
Flaoyen A.
Penitrem and
thomitrem formation by Penicillium crustosum.
Mycopathologia. 2004
Apr;157(3):349-57. |
