| Source: | Streptomyces diastatochromogenes |
| Synonyms | Oligomycin B
Oligomycin A, 28-oxo-
EINECS 234-275-5
|
| Description: | Oligomycin B: a macrolide antibiotic that inhibits membrane bound mitochondrial ATPase.
Practically free of homologs |
| CAS number: | 11050-94-5 |
| Merck index: | 12, 6970 |
| Molecular weight: | 841.08 |
| Structure: | 
(Oligomycin B)
 |
| Molecular Formula: |
C45H72O12 |
| Canonical SMILES |
CCC1CCC2C(C(C(C3(O2)C(=O)CC(C(O3)CC(C)O)C)C)OC(=O)C=CC(C(C(C(=O)C(C(C(C(=O)C(C(C(CC=CC=C1)C)O)(C)O)C)O)C)C)O)C)C |
Solubility
information: | Dichloromethane, DMSO, Ethanol, Acetone |
| Specifications | |
| Appearance: | White powder |
| Purity: | At least 97% by TLC, HPLC |
| λmax: | 225 |
| Melting point | 156°C-164°C |
| Solubility | Clear colorless solution at 5 mg/ml Methanol, 5 mg/ml Acetonitril |
| Storage | +4°C or below |
| Applications | Used as a tool in cytochemistry |
| Warnings | |
| Classification | macrolide
ATPase inhibitor |
| Related products |
Oligomycin complex , Oligomycin A , Oligomycin B
|
| | For Research use only. Not for Human or Drug use
GMP/API grade available on request
No genetically modified organisms are used. |
| Publications | |
| | Prouty WF, Thompson RM, Schnoes HK, Strong FM.
Oligomycin: degradation products and part structure of oligomycin B 1 .
Biochem Biophys Res Commun. 1971 Aug 6;44(3):619-27.
PMID: 4107834 |
| | Three-dimensional structure of oligomycin B.
FEBS Lett. 1972 Feb 15;20(3):267-269.
von Glehn M, Norrestam R, Kierkegaard P, Maron L, Ernster L.
PMID: 11946434 |
