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cancer research reagents

Oligomycin B

MSDSSample CoA
 
Source: Streptomyces diastatochromogenes
SynonymsOligomycin B
Oligomycin A, 28-oxo-
EINECS 234-275-5
Description: Oligomycin B: a macrolide antibiotic that inhibits membrane bound mitochondrial ATPase.
Practically free of homologs
CAS number: 11050-94-5
Merck index: 12, 6970
Molecular weight: 841.08
Structure:

structure of the oligomycin B

(Oligomycin B)

 

Molecular Formula: C45H72O12
Canonical SMILES CCC1CCC2C(C(C(C3(O2)C(=O)CC(C(O3)CC(C)O)C)C)OC(=O)C=CC(C(C(C(=O)C(C(C(C(=O)C(C(C(CC=CC=C1)C)O)(C)O)C)O)C)C)O)C)C
Solubility
information:
Dichloromethane, DMSO, Ethanol, Acetone
Specifications 
Appearance: White powder
Purity: At least 97% by TLC, HPLC
λmax:225
Melting point156°C-164°C
SolubilityClear colorless  solution at 5 mg/ml Methanol, 5 mg/ml Acetonitril
Storage+4°C or below
ApplicationsUsed as a tool in cytochemistry
Warnings
Classificationmacrolide
ATPase inhibitor
Related products
  Oligomycin complex ,  Oligomycin A ,  Oligomycin B
 For Research use only. Not for Human or Drug use
GMP/API grade available on request


No genetically modified organisms are used.
Publications 
 Prouty WF, Thompson RM, Schnoes HK, Strong FM.
Oligomycin: degradation products and part structure of oligomycin B 1 .
Biochem Biophys Res Commun. 1971 Aug 6;44(3):619-27.
PMID: 4107834
 Three-dimensional structure of oligomycin B.
FEBS Lett. 1972 Feb 15;20(3):267-269.
von Glehn M, Norrestam R, Kierkegaard P, Maron L, Ernster L.
PMID: 11946434

Oligomycin on Wikipedia
 


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 Oligomycin B