| Source: | Streptomyces diastatochromogenes |
| Synonyms | EINECS 209-437-3 |
| Description: | Oligomycin A: a macrolide antibiotic that inhibits membrane bound mitochondrial ATPase.
Practically free of homologs |
| CAS number: | 579-13-5 |
| Merck index: | 13,6902 |
| Molecular weight: | 791.06 |
| Structure: | 
Oligomycin A
 |
| Molecular Formula: | C45H74O11 |
| Canonical SMILES |
CCC1CCC2C(C(C(C3(O2)CCC(C(O3)CC(C)O)C)C)OC(=O)C=CC(C(C(C(=O)C(C(C(C(=O)C(C(C(CC=CC=C1)C)O)(C)O)C)O)C)C)O)C)C |
Solubility
information: | Dichloromethane, DMSO, Ethanol, Acetone |
| Specifications | |
| Appearance: | White powder |
| Purity: | At least 97% by TLC, HPLC |
| λmax: | 225 |
| Melting point | 148°C-152°C |
| Solubility | Clear colorless solution at 10 mg/ml Methanol, 10mg/ml Dichloromethane |
| Storage | +4°C or below |
| Applications | Used as a tool in cytochemistry |
| Warnings | |
| Classification | macrolide
ATPase inhibitor |
| Related products |
Oligomycin complex , Oligomycin A , Oligomycin B
|
| | For Research use only. Not for Human or Drug use
GMP/API grade available on request
No genetically modified organisms are used. |
| Publications | |
| | Tettamanti G, Malagoli D, Marchesini E, Congiu T, de Eguileor M, Ottaviani E.
Oligomycin A induces autophagy in the IPLB-LdFB insect cell line.
Cell Tissue Res. 2006 Oct;326(1):179-86. |
| | Roberton AM, Holloway CT, Knight IG, Beechey RB.
A comparison of the effects of NN'-dicyclohexylcarbodi-imide, oligomycin A and aurovertin on enrgy-linked reactions in mitochondria and submitochondrial particles.
Biochem J. 1968 Jul;108(3):445-56.
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