| Source: | Penicillium brevicompactum |
| Synonyms | |
| Description: | Mycophenolic acid: an immunosupressor. Purine nucleotide synthesis inhibitor |
| CAS number: | 24280-93-1 |
| Merck index: | 11, 6238 |
| Molecular weight: | 320.3 |
| Structure: | 
 |
| Molecular Formula: | C17H20O6 |
| Canonical SMILES: |
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Solubility
information: | DMSO, Ethanol, Methanol, Dichloromethane. Insoluble in water |
| Specifications |
|
| Appearance: | off-white powder. |
| Purity: | At least 98% by TLC, HPLC |
| λmax: | 304 |
| Melting point | 138°C-142°C |
| Solubility | Clear colorless solution at 10mg/ml Methanol |
| Storage | +4°C. |
| Applications | |
| Warnings | Harmful by inhalation, in contact with skin and if swallowed. |
| Classification | fatty
acid antibiotic |
| Related products |
Rapamycin,
Ascomycin,
FK506,
Mycophenolate
mofetil |
| | For Research use only. Not for Human or Drug use
GMP/API grade available on request
No genetically modified organisms are used.Raw materials from animal origin info |
| Publications | |
| | Westley IS, Morris RG, Evans AM, Sallustio BC.
Glucuronidation of mycophenolic acid by Wistar and Mrp2 deficient TR- rat liver microsomes.
Drug Metab Dispos. 2007 Oct 1 |
| | Wada K, Takada M, Kotake T, Ochi H, Morishita H, Komamura K, Oda N, Mano A, Kato TS, Hanatani A, Nakatani T.
Limited sampling strategy for mycophenolic acid in Japanese heart transplant recipients: comparison of cyclosporin and tacrolimus treatment.
Circ J. 2007 Jul;71(7):1022-8. |
| | Takekuma Y, Kakiuchi H, Yamazaki K, Miyauchi S, Kikukawa T, Kamo N, Ganapathy V, Sugawara M.
Difference between pharmacokinetics of mycophenolic acid (MPA) in rats and that in humans is caused by different affinities of MRP2 to a glucuronized form
J Pharm Pharm Sci. 2007;10(1):71-85 |
| | Takada M, Wada K,Ueda T, Ochi H, Kotake T, Morishita H, Hanatani A, Nakatani T.
Relationship between acute rejection and cyclosporine or mycophenolic acid levels in Japanese heart transplantation.
Circ J. 2007 Mar;71(3):289-93. |
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| |  | |
| | See also United States Patent
7683188 |
|
