fermentek makes and sells biochemicals for research
Fermentek products delivered worldwide by courier
Fermentek homepage
support, sale policy, gmo, mad cow safety, privacy products
contact us
cancer research reagents

Ionomycin (Calcium salt)

MSDSSample CoA
Source: Streptomyces conglobatus
Description: Ionomycin : a  Ca++ ionophore
CAS number: 56092-82-1
Merck index:  
Molecular weight: 747.07

ionomycin Calcium salt structure


Molecular Formula: C41H70O9Ca
Canonical SMILES:  
DMSO, Ethanol, Methanol
Appearance: White to pale yellow crystalline solid.
Purity: At least 98% by TLC, HPLC         current lot : 99.2% by HPLC
Melting point204C-206C
SolubilityClear colorless solution at  5 mg in 1 ml of DMSO
Storage+4C. Protect from light.
Applications Ionomycin is more effectivethan A23187 as a Ca++ionophore.
Ionomycin  is used in research on  Ca
++ transport across biological membranes;
Ionomycin induces apoptotic degeneration of embryonic cortical neurons
WarningsPotentially hazardous.. To our knowledge, the hazards of this material have not yet been thoroughly investigated.
ClassificationFatty acid antibiotic
Calcium Ionophore
Related productsAlso available as free acid
 For Research use only. Not for Human or Drug use
GMP/API grade available on request

No genetically modified organisms are used.
  Holmes AG, Watt MJ, Carey AL, Febbraio MA.
Ionomycin , but not physiologic doses of epinephrine, stimulates skeletal muscle interleukin-6 mRNA expression and protein release.
Metabolism. 2004 Nov;53(11):1492-5.
  McCollum AT, Jafarifar F, Chan R, Guttmann RP.
Oxidative stress inhibits ionomycin -mediated cell death in cortical neurons.
J Neurosci Res. 2004 Apr 1;76(1):104-9.
  Cavarra MS, Assef YA, Kotsias BA.
Effects of ionomycin and thapsigargin on ion currents in oocytes of Bufo arenarum.
J Exp Zoolog A Comp Exp Biol. 2003 Jun 1;297(2):130-7.
  Abramov AY, Duchen MR.
Actions of ionomycin, 4-BrA23187 and a novel electrogenic Ca2+ ionophore on mitochondria in intact cells.
Cell Calcium. 2003 Feb;33(2):101-12.
  Gil-Parrado S, Fernandez-Montalvan A, Assfalg-Machleidt I, Popp O, Bestvater F, Holloschi A, Knoch TA, Auerswald EA, Welsh K, Reed JC, Fritz H, Fuentes-Prior P, Spiess E, Salvesen GS, Machleidt W.
Ionomycin -activated calpain triggers apoptosis. A probable role for Bcl-2 family members.
J Biol Chem. 2002 Jul 26;277(30):27217-26





Home Hebrew About  us ISO GMP/API Products Mad cow Sales policy Receiving RFQ Ask scientistContact salesPrivacy  About website 


7AAD17AAG17DMAGA23187 ActinomycinAflatoxin B1Aflatoxin B2Aflatoxin M1AlamethicinAnisomycinApicidinAphidicolinAscomycin
Bafilomycin Brefeldin CastanospermineCeruleninChelerythrineChromomycin A3CitreoviridinCitrininCyclopamineCytochalasin ACytochalasin B
Cytochalasin CCytochalasin DCytochalasin EDihidrocytochalasinDeoxynivalenolDiacetoxyscirpenolFK506ForskolinFumagillinFumonisinGeldanamycin
GliotoxinHypericinHT2 toxinIonomycinK252AK252CKT5720KT5823Leptomycin BMithramycin AMoniliforminMycophenolicMyriocinNigericin
NonactinOchratoxin AOligomycinParthenolidePatulinPaxillinePenicillic acidPenitremPKC412PuromycinPuromycin ANRadicicolStaurosporine
SterigmatocystinT2 toxinTentnoxinThapsigarginThiolutinThiostreptonTriacsinTrichostatinTunicamycinValinomycinVerruculogenVomitoxin
Withaferin WortmanninZearalenone


unique visitor counter
Company's eMail: 

Anti-spam measures have been taken here. Please copy this address into your eMail software. We are sorry for the inconvenience.

Mail Address:
Yatziv 25, Atarot industrial zone,
POB 47120, Jerusalem 97800 Israel
Fax:     972 2 5853943
Phone: 972 2 5853953