| Source: | Hypericium perforatum ( plant extract ) |
| Synonyms | Cyclo-Werrol
EINECS 208-941-0
|
| Description: | Hypericin is an anti-retroviral agent. A protein kinaze-C inhibitor. |
| CAS number: | 548-04-9 |
| Merck index: | 12, 4911 |
| Molecular weight: | 504.45 |
| Structure: | 
 |
| Molecular Formula: | C30H16O8 |
| Canonical SMILES: |
|
Solubility
information: | Soluble in alkaline aqueous solutions. Soluble in organic bases such as pyridine (red fluorescent solutions) but not in other organic solvents |
| Specifications | |
| Appearance: |
|
| Purity: | At least 97% by TLC, HPLC |
| λmax: | (in methanol) 330, 370, 544 |
| Melting point | 320 (decomposition) |
| Solubility |
Clear red solution at
10mg/ ml DMSO
|
| Storage | +4°C. Protect from light. |
| Applications | Antidepressant. Apoptosis inducer. |
| Warnings | Potentially toxic, carcinogenic, teratogenic |
| Classification | Perylene analog.
PKC inhibitor.
Antiviral |
| Related products | |
| | For Research use only. Not for Human or Drug use
GMP/API grade available on request.
 Plant
extract. No
raw materials from
animal source were used.
Hypericin by Fermentek is not produced from or contains any ingredients from animal origin.
No genetically modified organisms are used. |
| Publications | |
| | Sobaci G, Bayraktar MZ, Karslioglu Y, Durukan AH, Hurmeric V, Aykas S.
Hypericin-enhanced argon laser photocoagulation for subfoveal choroidal neovascular membrane in age-related macular degeneration: a pilot study.
Eur J Ophthalmol. 2006 Jan-Feb;16(1):119-28. |
| | Dabrowski MJ, Maeda D, Zebala J, Lu WD, Mahajan S, Kavanagh TJ, Atkins WM.
Glutathione S-transferase P1-1 expression modulates sensitivity of human kidney 293 cells to photodynamic therapy with hypericin.
Arch Biochem Biophys. 2006 May 15;449(1-2):94-103. Epub 2006 Mar 3. |
| | Schulz HU, Schurer M, Bassler D, Weiser D.
Investigation of the effect on photosensitivity following multiple oral dosing of two different hypericum extracts in healthy men.
Arzneimittelforschung. 2006;56(3):212-21. |
| | |
