| Source: | Hypericium perforatum ( plant extract ) |
| Synonyms | Cyclo-Werrol |
| Description: | Hypericin is an anti-retroviral agent. A protein kinaze-C inhibitor. |
| CAS number: | 548-04-9 |
| Merck index: | 12, 4911 |
| Molecular weight: | 504.45 |
| Structure: | 
 |
| Molecular Formula: | C30H16O8 |
Solubility
information: | Soluble in alkaline aqueous solutions. Soluble in organic bases such as pyridine (red fluorescent solutions) but not in other organic solvents |
| Specifications | |
| Appearance: | White crystalline solid. |
| Purity: | At least 97% by TLC, HPLC |
| λmax: | (in methanol) 330, 370, 544 |
| Melting point | 320 (decomposition) |
| Solubility | |
| Storage | +4°C. Protect from light. |
| Applications | Antidepressant. Apoptosis inducer. |
| Warnings | Potentially toxic, carcinogenic, teratogenic |
| Classification | Peryleneanalog.
PKC inhibitor.
Antiviral |
| Related products | |
| | For Research use only. Not for Human or Drug use
GMP/API grade available on request
Hypericin by Fermentek is not produced from or contains any ingredients from animal origin.
No genetically modified organisms are used. |
| Publications | |
| | Sobaci G, Bayraktar MZ, Karslioglu Y, Durukan AH, Hurmeric V, Aykas S.
Hypericin-enhanced argon laser photocoagulation for subfoveal choroidal neovascular membrane in age-related macular degeneration: a pilot study.
Eur J Ophthalmol. 2006 Jan-Feb;16(1):119-28. |
| | Dabrowski MJ, Maeda D, Zebala J, Lu WD, Mahajan S, Kavanagh TJ, Atkins WM.
Glutathione S-transferase P1-1 expression modulates sensitivity of human kidney 293 cells to photodynamic therapy with hypericin.
Arch Biochem Biophys. 2006 May 15;449(1-2):94-103. Epub 2006 Mar 3. |
| | Schulz HU, Schurer M, Bassler D, Weiser D.
Investigation of the effect on photosensitivity following multiple oral dosing of two different hypericum extracts in healthy men.
Arzneimittelforschung. 2006;56(3):212-21. |
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