| Source: | Soy bean (plant extract) |
| Synonyms | 4′,5,7-Trihydroxyisoflavone |
| Description: | Genistein: an isoflavone with anticancer, antiproliferation, and chemopreventive effects. Genistein induces cell differentiation. Genistein
inhibits protein histidine kinase. |
| CAS number: | 446-72-0 |
| Merck index: | 13, 4402 |
| Molecular weight: | 270.2 |
| Structure: | 
 |
| Molecular Formula: |
C15H10O5 |
Solubility
information: | Genistein is soluble in DMSO, Ethanol. |
| Specifications | |
| Appearance: | White solid. |
| Purity: | At least 98% by TLC, HPLC |
| λmax: | 262 |
| Melting point | |
| Solubility | Clear colorless solution at 50mg/ml DMSO |
| Storage | -20°C. Protect from light. |
| Applications | -20°C. |
| Warnings | TOXIC. POTENTIAL CARCINOGEN |
| Classification | isoflavonoid
histidine kinase inhibitor |
| Related products | |
| | For Research use only. Not for Human or Drug use
No genetically modified organisms are used. |
| Publications | |
| | Yang Y, Fix D.
Genetic analysis of the anti-mutagenic effect of genistein in Escherichia coli.
Mutat Res. 2006 Jul 25 |
| | Valero MS, Garay RP, Gros P, Alda JO.
Cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel and Na-K-Cl cotransporter NKCC1 isoform mediate the vasorelaxant action of genistein in isolated rat aorta.
Eur J Pharmacol. 2006 Jun 28 |
| | Hong H, Landauer MR, Foriska MA, Ledney GD.
Antibacterial activity of the soy isoflavone genistein.
J Basic Microbiol. 2006;46(4):329-35 |
| | Lee JS.
Effects of soy protein and genistein on blood glucose, antioxidant enzyme activities, and lipid profile in streptozotocin-induced diabetic rats.
Life Sci. 2006 Jun 23 |
| | Chen WF, Wong MS.
Genistein modulates the effects of parathyroid hormone in human osteoblastic SaOS-2 cells.
Br J Nutr. 2006 Jun;95(6):1039-47 |
