| Source: | Semisynthetic derivate of Cytochalasin B, obtained from Drechslera dematoidea. |
| Synonyms | |
| Description: | |
| CAS number: | 39156-67-7 |
| Merck index: | 13: 2819 |
| Molecular weight: | 481.6 |
| Structure: | 
 |
| Molecular Formula: | C29H39NO5 |
| Canonical SMILES: |
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Solubility
information: | Acetone, DMSO, 100% Ethanol, Methanol |
| Specifications | |
| Appearance: | White powder |
| Purity: | At least 98% by TLC, HPLC |
| λmax: | |
| Melting point | 203ºC - 205ºC |
| Solubility | Clear colorless solution at 10mg/ml Methanol |
| Storage | -20°C. Protect from light. |
| Applications | Cytochalasins are used as tools in cytological research, and in in the field of actin polymerisation |
| Warnings | TOXIC. POTENTIAL CARCINOGEN. HARMFUL IF SWALLOWED |
| Classification | Macrolide indol mycotoxin
Cytochalasin
Actin inhibitor |
| Related products | Cytochalasin A, Cytochalasin B, Dihydro-Cytochalasin B, Cytochalasin C, Cytochalasin D, Cytochalasin E |
| | For Research use only. Not for Human or Drug use
GMP/API grade available on request
Dihydrocytochalasin B by Fermentek is not produced from or contains any ingredients from animal origin.
No genetically modified organisms are used. |
| Publications | |
| | Dijkstra J, van Galen M, Scherphof G.
Effects of dihydro-cytochalasin B, colchicine, monensin and trifluoperazine on uptake and processing of liposomes by Kupffer cells in culture.
Biochim Biophys Acta. 1985 Apr 22;845(1):34-42 |
| | Freyria AM, Ronziere MC, Roche S, Rousseau CF, Herbage D.
Regulation of growth, protein synthesis, and maturation of fetal bovine epiphyseal chondrocytes grown in high-density culture in the presence of ascorbic acid, retinoic acid, and dihydrocytochalasin B.
J Cell Biochem. 1999 Nov;76(1):84-98. |
| | PD Benya, PD Brown and SR Padilla
Microfilament modification by dihydro-cytochalasin B causes retinoic acid-modulated chondrocytes to reexpress the differentiated collagen phenotype without a change in shape
The Journal of Cell Biology, Vol 106, 161-170 |
