| Source: | Drechslera dematoidea |
| Synonyms | |
| Description: | Cytochalasin A is a fungal toxin which inhibits glucose transport, actine
polymerization and blocks the formation of microtubuli. Inhibits cell division. Inhibits HIV-1 protease |
| CAS number: | 14110-64-6 |
| Merck index: | 13, 2819 |
| Molecular weight: | 477.6 |
| Structure: | 
 |
| Molecular Formula: | C29H35NO5 |
| Canonical SMILES: |
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Solubility
information: | DMSO, Acetone, Ethanol. |
| Specifications | |
| Appearance: | White powder. |
| Purity: | At least 98% by TLC, HPLC |
| λmax: | |
| Melting point | |
| Solubility | Clear colorless solution at 5 mg/ml of acetone |
| Storage | -20°C. Protect from light. |
| Applications | Cytochalasins are used as tools in cytological research, and in the field of actin
polymerization |
| Warnings | Hazardous. |
| Classification | Macrolide indol
mycotoxin
Cytochalasin
Actin inhibitor |
| Related products | Cytochalasin A, Cytochalasin B, Dihydro-Cytochalasin B, Cytochalasin C, Cytochalasin D, Cytochalasin E |
| | For Research use only. Not for Human or Drug use
GMP/API grade available on request
Cytochalasin A by Fermentek is not produced from or contains any ingredients from animal origin.
No genetically modified organisms are used. |
| Publications | |
| | Sugimoto M, Toyoda K, Ichinose Y, Yamada T, Shiraishi T.
Cytochalasin A inhibits the binding of phenylalanine ammonia-lyase mRNA to ribosomes during induction of phytoalexin in pea seedlings.
Plant Cell Physiol. 2000 Feb;41(2):234-8. |
| | Torralba S, Raudaskoski M, Pedregosa AM, Laborda F.
Effect of
Cytochalasin A on apical growth, actin cytoskeleton organization and enzyme secretion in Aspergillus nidulans.
Microbiology. 1998 Jan;144 ( Pt 1):45-53. |
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