Aflatoxin M1

MSDSSample CoA
 

Source: Aspergillus flavus Synonyms 4-hydroxyaflatoxin B1 EINECS 229-865-4 Description: Aflatoxin M1 is a  potent hepatotoxic and hepatocarcinogenic mycotoxin, found in milk of cows fed on meal contaminated with Aflatoxin B1 CAS number: 6795-23-9 Merck index: 12, 180 Molecular weight: 328.3 Structure: Molecular Formula: C17H1207 Canonical SMILES: COC1=C2C3=C(C(=O)CC3)C(=O)OC2=C4C(=C1)OC5C4(C=CO5)O Solubility information: Methanol, DMSO Specifications   Appearance: Off - white powder. Blue-violet fluorescence Purity: At least 98% by TLC, HPLC λmax: 228, 264, 360nm Melting point   Solubility   Storage 4°C. Protect from light. Applications Potent liver carcinogen and DNA-damaging agent. It is also mutagenic, teratogenic, and causes immunosuppression in animals. Warnings TOXIC. CARCINOGEN Classification Furano-furano-Benzopyranmycotoxin Aflatoxin Related products Aflatoxin B1 , B2, G1, G2, M1, M2   For Research use only. Not for Human or Drug use GMP/API grade available on request No genetically modified organisms are used. Publications     Muscarella M, Lo Magro S, Palermo C, Centonze D. Validation according to European Commission Decision 2002/657/EC of a confirmatory method for aflatoxin M1 in milk based on immunoaffinity columns and high performance liquid chromatography with fluorescence detection. Anal Chim Acta. 2007 Jul 2;594(2):257-64.   Boudra H, Barnouin J, Dragacci S, Morgavi DP. Aflatoxin M1 and ochratoxin A in raw bulk milk from French dairy herds. J Dairy Sci. 2007 Jul;90(7):3197-201.   Tajkarimi M, Shojaee Aliabadi F, Salah Nejad M, Pursoltani H, Motallebi AA, Mahdavi H. Seasonal study of aflatoxin M1 contamination in milk in five regions in Iran. Int J Food Microbiol. 2007 May 30;116(3):346-9. Epub 2007 Mar 1.   Polychronaki N, West RM, Turner PC, Amra H, Abdel-Wahhab M, Mykkanen H, El-Nezami H. A longitudinal assessment of aflatoxin M1 excretion in breast milk of selected Egyptian mothers. Food Chem Toxicol. 2007 Jul;45(7):1210-5.   Zinedine A, Gonzalez-Osnaya L, Soriano JM, Molto JC, Idrissi L, Manes J. Presence of aflatoxin M1 in pasteurized milk from Morocco. Int J Food Microbiol. 2007 Feb 28;114(1):25-9.

AVAILABLE Standard solutions  Aflatoxin M1 solution Aspergillus flavus culture on agar plate INCHEM Aflatoxin M1 review   ...The European Community supports the maximum level of 0.05 μg/kg for aflatoxin M1 in liquid milk... ...there is sufficient evidence that aflatoxin M1 is a genotoxic carcinogen; its carcinogenic potency is estimated to be approximately 10 times lower than aflatoxin B1... CODEX COMMITTEE ON FOOD ADDITIVES AND CONTAMINANTS 20-24 March 2000 Aflatoxin on Wikipedia