| Source: |
Fusarium sp. |
| Synonyms |
8-Hydroxydiacetoxyscirpenol
Trichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol, 12,13-epoxy-,
4,15-diacetate |
| Description: |
Type A trichothecene mycotoxin |
| CAS number: |
36519-25-2
Attention: also listed under
CAS number 65041-92-1 |
| Merck index: |
14: Not listed |
| Molecular weight: |
382.4 |
| Structure: |
 |
| Molecular Formula: |
C19H26O8 |
Solubility
information: | |
| Specifications | |
| Appearance: |
Slight yellow powder |
| Purity |
-
TLC (Toluene: Ethyl
acetate: Acetic acid 6:3:1)gives single spot
-
TLC (CH2Cl2:
Methanol 95: 5) gives
single spot
-
TLC (RP C18,
Methanol: H2O 8: 2) gives single spot
(Detection by
spraying with H2SO4 and heat) |
| λmax: | |
| Melting point |
176 -
178ºC |
| Solubility |
-
Clear colorless solution at 10mg/ml CH2Cl2
-
Clear colorless solution at10mg/ml
methanol
-
Clear colorless solution at 10mg/ml DMSO
|
| Storage |
-18°C. |
| Classification |
trichothecene mycotoxin |
| Applications |
All trichocenes have strong impact on the
health due to their immunosuppressive properties |
| Warnings | |
| Related products |
Diacetoxyscirpenol
,
|
| | Neosolaniolis intended for Research use only.
Not for Human or Drug use
GMP/API grade available on request
Neosolaniolfrom Fermentek is not produced from or contains any ingredients from animal origin.
No genetically modified organisms are used. |
| Publications |
|
| |
Janse van Rensburg DF, Thiel PG, Jaskiewicz K.
Short-term effects of
two fusarium toxins, diacetoxyscirpenol and neosolaniol monoacetate,
in male Wistar rats.
Food Chem Toxicol. 1987 Oct;25(10):767-71. |
| |
Anderson DW, Black RM, Lee CG, Pottage C, Rickard RL, Sandford MS,
Webber TD, Williams NE.
Structure-activity studies of trichothecenes:
cytotoxicity of
analogues and reaction products derived from T-2 toxin and
neosolaniol.
J Med Chem. 1989 Mar;32(3):555-62. |
| |
