| | Section 1. Product and Company Information |
| Name: | Valinomycin |
| CAS Number: | 2001-95-8 |
| Catalog Code: | Valinomycin |
| Company Identification | Fermentek ltd, See page footer for contact details |
| | Section 2. Composition/Information on Ingredient |
| EINECS/ELINCS | 217-896-6 |
| Chemical Formula: | C17H22N2O3 |
| Chemical Class: | |
| RTECS | YV9468000 |
| TSCA | |
| | Section 3. Hazards Identification |
| Potential Acute Health Effects | Very hazardous in case of skin contact (permeator), of ingestion, of inhalation. Slightly hazardous in case of skin contact (irritant), of eye contact (irritant). Severe over-exposure can result in death |
| Potential Chronic Health Effects | The substance may be toxic to the nervous system, peripheral nervous system, central nervous system (CNS), eye, lens or cornea. Repeated or prolonged exposure to the substance can produce target organs damage. Repeated exposure to a highly toxic material may produce general deterioration of health by an accumulation in one or many human organs. |
| | Section 4. First Aid Measures |
| Eye Contact | Check for and remove contact lenses. Flush eyes with running water for at least 15 minutes separating eyelids. Seek medical attention immediately. |
| Skin Contact | Wash with soap and water for 15 minutes. Remove contaminated clothing and shoes. Seek medical attention immediately |
| Inhalation | Remove from exposure. If breathing is difficult, administer oxygen. If breathing stops, administer artificial respiration. Seek medical attention immediately. Provide chemical label and MSDS if possible. |
| Ingestion | Remove dentures and clear mouth. If person is conscious, rinse mouth with water Call physician or poison control immediately. Provide chemical label and MSDS information if possible. |
| | Section 5. Fire and Explosion Data |
| Flammability | Not Available |
| Flash Point | Not Available |
| Combustion products | CO, CO2, NO,NO2, |
| Extinguishing Media | Carbon Dioxide, Dry chemical powder, polymer foam, water spray |
Special Firefighting Procedures | Use self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes. |
| Unusual Fire/Explosion Hazards | None known |
| | Section 6 - Accidental Release Measures |
| Cleanup Procedures | Wearing appropriate protective gear as outlined under “Protective equipment” wipe up spill and place in sealed container and hold for disposal. Avoid raising dust. Ventilate the area and wash spill site after material has been removed |
Waste Disposal Method | Observe all Federal, State and Local regulations concerning the disposal of this product. Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete |
| | Section 7 - Handling and Storage |
| Protective Equipment | For spill clean up, wear suitable protective clothing, chemical resistant rubber gloves, rubber boots, and chemical safety goggles. Self contained breathing apparatus or NIOSH/MSHA approved respirator is recommended. |
| Storage and Handling | This product should be kept in a tightly closed container. This product should be handled only by qualified experienced professionals. Wash thoroughly after handling this material Store at -18oC |
| | Section 8 - Exposure Controls / Personal protection |
| General | Use only in a chemical fume hood. Safety shower and eye bath. Use adequate ventilation to keep airborne concentrations low |
| Personal protective equipment | - Respiratory: Government approved respirator.
- Hand: Compatible chemical-resistant gloves.
- Eye:Chemical safety goggles.
|
| | Section 9. Physical Data |
| Appearance | Off white powder |
| Molecular Weight | 1111.4 |
| Solubility | DMSO, Ethanol, petrol ether. Not soluble in water |
| | Section 10. Stability and Reactivity Data |
| Stability | This material is stable if stored as directed |
| Conditions to Avoid | Excess heat, incompatible materials, strong oxidizers |
| Incompatibles | Reactive with oxidizing agents, acids, alkalis. |
| Hazardous polymerization | Will not occur |
| | Section 11 - Toxicological Information |
| RTECS#: | YV9468000 |
| Routes of Entry | Absorbed through skin. Dermal contact. Inhalation. Ingestion. |
| Toxicity to Animals | Acute oral toxicity (LD50): 2.5 mg/kg [Mouse] Acute dermal toxicity (LD50): 5 mg/kg [Rabbit]. |
| Chronic Effects on Humans: | May cause damage to the following organs: the nervous system, peripheral nervous system, central nervous system (CNS), eye, lens or cornea. |
| Other Toxic Effects on Humans | Very hazardous in case of skin contact (permeator), of ingestion, of inhalation. Slightly hazardous in case of skin contact (irritant). |
| Special Remarks on other Toxic Effects on Humans | |
| Acute Potential Health Effects | May cause skin irritation. May be fatal if absorbed through skin. May affect behavior/central nervous system if absorbed through skin with symptoms similar to that of ingestion. It may also affect metabolism (weight loss) |
| Eyes | May cause eye irritation. High exposure may cause, corneal edema, intraocular pressure, clouding of the eye lenses (cataracts) with loss of vision. |
| Inhalation | May be harmful if inhaled |
| Ingestion | May be fatal if ingested. May affect behavior/central nervous system (tremors, convulsions/seizures, aggressive behavior) and peripherial nervous system. It may also affect the heart and kidneys as is seen with other ionophore antibiotics. |
| Chronic Potential Health Effects | |
| Ingestion | Prolonged or repeated ingestion may affect behavior/central nervous system with symptoms similar to that of acute ingestion. |
| | Section 12 - Ecological Data |
| Ecotoxicological Information: | None Available |
| | Section 13 - Disposal Considerations |
| Appropriate method of disposal of substance or preparation | Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Observe all federal, state, and local environmental regulations. Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification. |
| | Section 14 - Transport Information |
| US DOT | CLASS 6.1: Poisonous material |
| Identification | Toxic Solid, organic, n.o.s.(Valinomycin) UNNA: 2811 PG: I |
| | Section 15-Regulatory Information |
| TSCA 8(b) inventory | Valinomycin |
| SARA | 302/304/311/312 extremely hazardous substances: Valinomycin |
| CERCLA | Hazardous substances.: Valinomycin: 1000 lbs. (453.6 kg) |
| OSHA | Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200) |
| EINECS | This product is on the European Inventory of Existing Commercial Chemical Substances. |
| Other Classifications | |
| WHMIS (Canada): | CLASS D-1A: Material causing immediate and serious toxic effects (VERY TOXIC) |
| DSCL (EEC): | R27/28- Very toxic in contact with skin and if swallowed. S36/37- Wear suitable protective clothing and gloves. S45- In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). |
| HMIS (U.S.A.) | Health Hazard: 3, Fire Hazard: 1, Reactivity: 0, Personal Protection: E |
| National Fire Protection Association (U.S.A.) | Health: 3,Flammability: 1, Reactivity: 0 Protective Equipment:Gloves.Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Wear appropriate respirator when ventilation is inadequate. Safety glasses. |
| | Section 16 -Other Information |
| Disclaimer | For R&D use only. Not for drug, household or other uses |
| Warranty | DISCLAIMER For R&D use only. Not for drug, household or other uses. For use only by trained personnel. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. The burden of safe use of this material rests entirely with the user. Fermentek shall not be held liable or any damage resulting from handling or from contact with the above product.
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