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cancer research reagents

MSDS for Trichostatin A

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Section 1. Product and Company Information
Name: TRICHOSTATIN A
CAS Number: 58880-19-6
Catalog Code:
Company Identification Fermentek ltd, See page footer for contact details
Section 2. Composition/Information on Ingredient
EINECS/ELINCS

Not listed

Chemical Formula: C17H22N2O3
Chemical Class:
RTECS
TSCA
Section 3. Hazards Identification
Special indication of hazards to humans and the environment
  • Harmful by inhalation, in contact with skin and if swallowed.

  • Irritating to eyes, respiratory system and skin. May cause

  • sensitization by skin contact.
Chronic Health Effects unknown
Section 4. First Aid Measures
Eye Contact Check for and remove contact lenses. Flush eyes with running water for at least 15 minutes separating eyelids. Seek medical attention immediately.
Skin Contact Wash with soap and water for 15 minutes. Remove contaminated clothing and shoes. Seek medical attention immediately
Inhalation Remove from exposure. If breathing is difficult, administer oxygen. If breathing stops, administer artificial respiration. Seek medical attention immediately. Provide chemical label and MSDS if possible.
Ingestion Remove dentures and clear mouth. If person is conscious, rinse mouth with water Call physician or poison control immediately. Provide chemical label and MSDS information if possible.
Section 5. Fire and Explosion Data
Flammability Not Available
Flash Point Not Available
Combustion Products CO, CO2, NO,NO2,
Extinguishing Media Carbon Dioxide, Dry chemical powder, polymer foam, water spray
Special Firefighting Procedures Use self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Unusual Fire/Explosion Hazards None known
Section 6 - Accidental Release Measures
Cleanup Procedures Wearing appropriate protective gear as outlined under “Protective equipment” wipe up spill and place in sealed container and hold for disposal. Avoid raising dust. Ventilate the area and wash spill site after material has been removed

Waste Disposal Method

  • Observe all Federal, State and Local regulations concerning the disposal of this product.
  • Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete
Section 7 - Handling and Storage
Protective Equipment For spill clean up, wear suitable protective clothing, chemical resistant rubber gloves, rubber boots, and chemical safety goggles. Self contained breathing apparatus or NIOSH/MSHA approved respirator is recommended.
Storage and Handling This product should be kept in a tightly closed container. This product should be handled only by qualified experienced professionals. Wash thoroughly after handling this material Store at -18oC
Section 8 - Exposure Controls / Personal protection
General Use only in a chemical fume hood. Safety shower and eye bath. Use adequate ventilation to keep airborne concentrations low
Personal protective equipment

  • Respiratory: Government approved respirator.
  • Hand: Compatible chemical-resistant gloves.
  • Eye:Chemical safety goggles.
Section 9. Physical Data
Appearance Off white powder
Molecular Weight 280.4
Solubility DMSO, Ethanol
Section 10. Stability and Reactivity Data
Stability This material is stable if stored as directed
Conditions to Avoid Excess heat, incompatible materials, strong oxidizers
Incompatibles Not Available
Hazardous polymerization Will not occur
Section 11 - Toxicological Information
RTECS#: MI521500
Acute toxicity: none known
Primary irritant effect
Sensitization Skin: May cause allergic skin reaction
Signs and sympromps of exposure Exposure can cause: Headache. Dizziness. To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated
Route of exposure Inhalation: Material is irritating to mucous membranes and upper respiratory tract
Multiple routes

Harmful if swallowed, inhaled, or absorbed through skin. Causes eye and skin irritation

Target organ information Central nervous system. Kidneys. Liver. G.I. System. Skeletal muscle. Cardiovascular system
Chronic exposure mutagen: Rat 100 UG/L, Cell Type: Embryo, DNA inhibition
Section 12 - Ecological Data
Ecotoxicological Information: None Available
Section 13 - Disposal Considerations
Appropriate method of disposal of substance or preparation

Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Observe all federal, state, and local environmental regulations. Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.

Section 14 - Transport Information
Non-Hazardous for transport This substance is considered to be non-hazardous for transport
US DOT Not regulated
Section 16 - Other Information
Disclaimer For R&D use only. Not for drug, household or other uses
Warranty

DISCLAIMER

For R&D use only. Not for drug, household or other uses. For use only by trained personnel.

The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. The burden of safe use of this material rests entirely with the user. Fermentek shall not be held liable or any damage resulting from handling or from contact with the above product.


    
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