| | Section 1. Product and Company Information |
| Name: | Ochratoxin A |
| CAS Number: | 303-47-9 |
| Catalog Code: | OC |
| Synonyms | (-)-N-((5-Chloro-8-hydroxy-3-methyl-1-oxo-7-isochromanyl)carbonyl)-3-phenylalanine |
| Company Identification | Fermentek ltd, See page footer for contact details |
| | Section 2. Composition/Information on Ingredient |
| EINECS/ELINCS | 206-143-7 |
| Chemical Formula: | C20-H18-Cl-N-O6 |
| Chemical Class: | |
| RTECS | AY4375000 |
| TSCA | not listed |
| | Section 3. Hazards Identification |
| Hazards overview | - Very hazardous in case of ingestion, of inhalation. Hazardous in case of skin contact (permeator), of eye contact (irritant).
- Slightly hazardous in case of skin contact (irritant).
- Severe over-exposure can result in death.
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| Potential Chronic Health Effects | - CARCINOGENIC EFFECTS: Classified 2B (Possible for human.) by IARC.
- MUTAGENIC EFFECTS: Mutagenic for bacteria and/or yeast.
- TERATOGENIC EFFECTS: Classified POSSIBLE for human
- The substance may be toxic to kidneys
- Repeated or prolonged exposure to the substance can produce target organs damage. Repeated exposure to a highly toxic material may produce general deterioration of health by an accumulation in one or many human organs
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| HMIS rating | Health Hazard: 3; Fire Hazard: 1; Reactivity: 0; Personal Protection: E |
| | Section 4. First Aid Measures |
| Eye Contact | Check for and remove contact lenses. Flush eyes with running water for at least 15 minutes separating eyelids. Seek medical attention immediately. |
| Skin Contact | Wash with soap and water for 15 minutes. Remove contaminated clothing and shoes. Seek medical attention immediately |
| Inhalation | Remove from exposure. If breathing is difficult, administer oxygen. If breathing stops, administer artificial respiration. Seek medical attention immediately. Provide chemical label and MSDS if possible. |
| Ingestion | Remove dentures and clear mouth. If person is conscious, rinse mouth with water Call physician or poison control immediately. Provide chemical label and MSDS information if possible. |
| | Section 5. Fire and Explosion Data |
| Flammability | Not Available |
| Flash Point | Not Available |
| Combustion products | CO, CO2, NO,NO2, |
| Extinguishing Media | Carbon Dioxide, Dry chemical powder, polymer foam, water spray |
Special Firefighting Procedures | Use self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes. |
| Unusual Fire/Explosion Hazards | None known |
| | Section 6 - Accidental Release Measures |
| Cleanup Procedures | Wearing appropriate protective gear as outlined under “Protective equipment” wipe up spill and place in sealed container and hold for disposal. Avoid raising dust. Ventilate the area and wash spill site after material has been removed |
Waste Disposal Method | Observe all Federal, State and Local regulations concerning the disposal of this product.Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete |
| | Section 7 - Handling and Storage |
| Protective Equipment | For spill clean up, wear suitable protective clothing, chemical resistant rubber gloves, rubber boots, and chemical safety goggles. Self contained breathing apparatus or NIOSH/MSHA approved respirator is recommended. |
| Storage and Handling | This product should be kept in a tightly closed container. This product should be handled only by qualified experienced professionals. Wash thoroughly after handling this material Store at -18oC |
| | Section 8 - Exposure Controls / Personal protection |
| General | Use only in a chemical fume hood. Safety shower and eye bath. Use adequate ventilation to keep airborne concentrations low |
| Personal protective equipment | Respiratory:Government approved respirator. Hand:Compatible chemical-resistant gloves. Eye:Chemical safety goggles. |
| | Section 9. Physical Data |
| Appearance | Yellow crystals. Blue fluorescence |
| Molecular Weight | 404 |
| Melting | 105°C-110°C |
| Solubility | DMSO, Methanol, Ethanol. |
| | Section 10. Stability and Reactivity Data |
| Stability | This material is stable if stored as directed |
| Conditions to Avoid | Excess heat, incompatible materials, strong oxidizers |
| Incompatibles | Reactive with oxidizing agents, acids, alkalis. |
| Hazardous polymerization | Will not occur |
| | Section 11 - Toxicological Information |
| RTECS#: | |
| Routes of Entry | Absorbed through skin. Dermal contact. Inhalation. Ingestion. |
| Toxicity to Animals | Oral, Rat, LD55= 20 mg/kg |
| Chronic Effects on Humans | - CARCINOGENIC EFFECTS: Classified 2B (Possible for human.) by IARC.
- MUTAGENIC EFFECTS: Mutagenic for bacteria and/or yeast
- TERATOGENIC EFFECTS: Classified POSSIBLE for human
- May cause damage to the following organs: kidneys
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| Other Toxic Effects on Humans | - Very hazardous in case of ingestion, of inhalation.
- Hazardous in case of skin contact (permeator).
- Slightly hazardous in case of skin contact (irritant)
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| Special Remarks on Chronic Effects on Humans | - May cause adverse reproductive effects (paternal effects and effects on fertility (fetotoxicity, post-implantation mortality)) and birth defects.
- May cause cancer.
- May affect genetic materia
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Acute Potential Human Health Effects | - Skin: May cause skin irritation. May be absorbed through skin.
- Eyes: May cause eye irritation. May cause conjunctivitis.
- Inhalation: May be fatal if inhaled. May cause respiratory tract irritation.
- Ingestion: May be fatal if swallowed. May cause digestive tract irritation with possible ulceratin or bleending from stomach. May affect the urinary system (kidneys), endocrine system, liver (necrosis, fatty liver degeneration, , blood, behavior (somnolence, altered sleep time, ataxia), respiration (acute pulmonary edema), metabolism, cardiovascular system.
- Chronic Potential Health Effects
- May cause Kidney damage
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| | Section 12 - Ecological Data |
| Ecotoxicological Information: | None Available |
| | Section 13 - Disposal Considerations |
| Appropriate method of disposal of substance or preparation | Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Observe all federal, state, and local environmental regulations. Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification. |
| | Section 14 - Transport Information |
| US DOT | - DOT Classification: CLASS 6.1: Poisonous material.
- Identification: : Toxic Solid, Organic, n.o.s.
- UNNA: 2811 PG: II
- Special Provisions for Transport: Not available.
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| | Section 15-Regulatory Information |
| Federal and State Regulations: | - California prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer, birth defects or other reproductive harm, which would require a warning under the statute: OchratoxinA
- California prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer which would require a warning under the statute: OchratoxinA
- California Director's List of Hazardous Substances: OchratoxinA
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| Other Regulations | - OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200)
- EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances
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Other Classifications: DSCL (EEC): | Risk statements - R28- Very toxic if swallowed.
- R36- Irritating to eyes.
- R40- Possible risks of irreversible effects.
- R63- Possible risk of harm to the unborn child.
- R26- Very toxic by inhalation.
Safety statements - Keep locked up and out of the reach of children.
- S28- After contact with skin, wash immediately with plenty of water.
- S36/37- Wear suitable protective clothing and gloves.
- S45- In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
- S46- If swallowed, seek medical advice immediately and show this container or label.
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| | Section 16 -Other Information |
| Disclaimer | For R&D use only. Not for drug, household or other uses |
| Warranty | DISCLAIMER For R&D use only. Not for drug, household or other uses. For use only by trained personnel. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. The burden of safe use of this material rests entirely with the user. Fermentek shall not be held liable or any damage resulting from handling or from contact with the above product.
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