| | Section 1. Product and Company Information |
| Name: | Citreoviridin |
| CAS Number: | 25425-12-1 |
| Catalog Code: | CI |
| Synonyms | Citreoviridin
A |
| Company Identification | Fermentek ltd, See page footer for contact details |
| | Section 2. Composition/Information on Ingredient |
| EINECS/ELINCS | Not
listed |
| Chemical Formula: | C23H30O6 |
| Chemical Class: |
Aurovertin class mycotoxin |
| RTECS | UQ1235000 |
| TSCA | |
| | Section 3. Hazards Identification |
| Label precautionary statements |
-
Highly toxic (USA)
-
Toxic (EU)
-
Toxic by inhalation, in contact
with skin and if swallowed.
-
Irritating
to eyes, respiratory system and skin.
-
Possible risk of harm to
the unborn child.
-
Danger: Poison
-
May
be fatal or cause blindness if swallowed. Vapor harmful.
-
Target organs:
-
In
case of accident or if you feel unwell, seek medical advice Immediately
-
In case of contact with
eyes, rinse immediately with plenty of water and seek medical advice.
-
Wear suitable protective
clothing, gloves and eye/face protection.
-
Do not breathe dust.
|
| | Section 4. First Aid Measures |
| Eye Contact | Check for and remove contact lenses. Flush eyes with running water for at least 15 minutes separating eyelids. Seek medical attention immediately. |
| Skin Contact | Wash with soap and water for 15 minutes. Remove contaminated clothing and shoes. Seek medical attention immediately |
| Inhalation | Remove from exposure. If breathing is difficult, administer oxygen. If breathing stops, administer artificial respiration. Seek medical attention immediately. Provide chemical label and MSDS if possible. |
| Ingestion | Remove dentures and clear mouth. If person is conscious, rinse mouth with water Call physician or poison control immediately. Provide chemical label and MSDS information if possible. |
| | Section 5. Fire and Explosion Data |
| Flammability | Not Available |
| Flash Point | Not Available |
| Combustion Products | CO, CO2 |
| Extinguishing Media |
Carbon
dioxide, dry chemical powder or appropriate foam. |
| Special Fire fighting Procedures | Use self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes. |
| Unusual Fire/Explosion Hazards | May emit toxic fumes under fire conditions. |
| | Section 6 - Accidental Release Measures |
| Cleanup Procedures | Wearing appropriate protective gear as outlined under “Protective equipment” wipe up spill and place in sealed container and hold for disposal. Avoid raising dust. Ventilate the area and wash spill site after material has been removed |
| Waste Disposal Method | Observe all Federal, State and Local regulations concerning the disposal of this product. Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete |
| | Section 7 - Handling and Storage |
| Protective Equipment | For spill clean up, wear suitable protective clothing, chemical resistant rubber gloves, rubber boots, and chemical safety goggles. Self contained breathing apparatus or NIOSH/MSHA approved respirator is recommended. |
| Storage and Handling | It should be kept in a tightly closed container. This product should be handled only by qualified experienced professionals. Wash thoroughly after handling this material. Store at -18oC |
| | Section 8 - Exposure Controls / Personal protection |
| General | Use only in a chemical fume hood. Safety shower and eye bath. Use adequate ventilation to keep airborne concentrations low |
| Personal protective equipment | Respiratory:
Government approved respirator. Hand: Compatible chemical-resistant gloves. Eye:Chemical safety goggles. |
| | Section 9. Physical Data |
| Appearance | white crystalline powder |
| Molecular Weight | 736.93 |
| Melting | 110+_3 oC |
| Solubility | Citreoviridin
is soluble in benzene, ethanol, chloroform, ether,
dichloromethane. Citreoviridin is hardly
soluble in water (enough to give it yellow color) and hexane |
| | Section 10. Stability and Reactivity Data |
| Stability | This material is stable if stored as directed |
| Conditions to Avoid | Excess heat, incompatible materials, strong oxidizers |
| Incompatibles | Reactive with oxidizing agents, acids, alkalis. |
| Hazardous polymerization | Will not occur |
| | Section 11 - Toxicological Information |
| RTECS#: | UQ1235000 |
| ACUTE EFFECTS |
-
May be fatal if
inhaled, swallowed, or absorbed through skin. Causes eye and skin
irritation.
-
Material is
irritating to mucous membranes and upper respiratory tract.
EXPOSURE CAN CAUSE:
-
Ascending
paralysis, vomiting, convulsions, respiratory arrest, cardiovascular
disturbances, hypothermia, labored breathing, coma, and death.
-
Damage to the
eyes
-
Damage to the
liver
-
Damage to the
heart damage to the kidneys
-
May cause
convulsions.
-
Target organ(s):
eyes kidneys liver heart nerves
|
| CHRONIC EFFECTS |
To the best of our
knowledge, the chemical, physical, and toxicological properties have not been
thoroughly investigated. |
| Toxity data |
Organism
Route |
LD50 |
Effect |
Source |
mouse
Intra peritoneal |
7.2 mg/kg |
Peripheral nerve and sensation: flaccid paralysis without anesthesia
(usually neuromuscular blockage)
behavioral: convulsions or effect on seizure threshold
lungs, thorax, or respiration: other changes |
Japanese Journal of Experimental Medicine. Vol. 42, Pg. 91, 1972.
Link to PubMed |
mouse
oral |
29 mg/kg |
Peripheral nerve and sensation: flaccid paralysis without anesthesia
(usually neuromuscular blockage)
behavioral: convulsions or effect on seizure threshold
lungs, thorax, or respiration: other changes |
Japanese Journal of Experimental Medicine. Vol. 42, Pg. 91, 1972.
Link to PubMed |
Mouse
Subcu taneous |
9.6 mg/kg |
Behavioral: changes in motor activity (specific assay)
lungs, thorax, or respiration: dyspnea |
Research Communications in Chemical Pathology and Pharmacology. Vol. 59,
Pg. 31, 1988.
Link to PubMed |
Rabbit
Intra venous |
5 mg/kg |
|
Research Communications in Chemical Pathology and Pharmacology. Vol. 59,
Pg. 31, 1988.
Link to PubMed |
Rat
Subcu taneous |
3.6 mg/kg |
Peripheral nerve and sensation: flaccid paralysis without anesthesia
(usually neuromuscular blockage)
lungs, thorax, or respiration: other changes |
Japanese Journal of Experimental Medicine. Vol. 42, Pg. 91, 1972.
Link to PubMed |
|
| Effects on Reproduction |
-
Effects
on fertility (post-implantation mortality)
-
Effects
on embryo or fetus (fetotoxicity) effects on embryo or fetus (fetal death)
-
Specific
developmental abnormalities (central nervous system) specific developmental
abnormalities (craniofacial)
|
| | Section 12 - Ecological Data |
| Ecotoxicological Information: | None Available |
| | Section 13 - Disposal Considerations |
| Appropriate method of disposal of substance or preparation | Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Observe all federal, state, and local environmental regulations. Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification. |
| | Section 14 - Transport Information |
| US DOT | |
| | Section 15-Regulatory Information |
| European information |
Caution:
Risk statements:
-
R 23/24/25 : Toxic by inhalation,
in contact
with skin
and if
swallowed.
-
R 36/37/38 : Irritating
to
eyes,
respiratory
system and
skin.
-
R 63: Possible risk of harm to the unborn child.
Safety statements
-
S 45: In
case
of accident
or
if
you
feel
unwell,
seek medical
advice immediately (show
the label where possible).
-
S 26: In
case
of contact
with
eyes,
rinse
immediately with
plenty
of water
and
seek
medical
advice.
-
S 36/37/39: Wear
suitable
protective clothing,
gloves
and
eye/face protection.
-
S 22: Do not breathe dust.
EPA
GENETOX
program
1988, negative |
|
U.S. INFORMATION
| |
| | Section 16 -Other Information |
| Disclaimer | For R&D use only. Not for drug, household or other uses |
| Warranty | DISCLAIMER For R&D use only. Not for drug, household or other uses. For use only by trained personnel. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. The burden of safe use of this material rests entirely with the user. Fermentek shall not be held liable or any damage resulting from handling or from contact with the above product.
|
