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cancer research reagents

MSDS for Alternariol

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Section 1. Product and Company Information

Name:

Alternariol

CAS Number:

641-38-3

Catalog Code:

Synonyms

RTECS: HP8757000
AOH
Systematic Name :  3,4,4'-Trihydroxy-6'-methyl-2-biphenylcarboxylic acid, gamma lactone

Company Identification

Fermentek ltd,

Website:  www.fermentek.co.il
25 Yatziv st,  Atarot industrial zone
POB 47120 Jerusalem 97800, Israel
Tel: +972 2 585395
Fax: +972 2 5853943
eMail       Fermentek@Fermentek.com

Section 2. Composition/Information on Ingredients

EINECS/ELINCS

not listed

Chemical Formula:

C14H10O5

Chemical Class:

Pyrrolidinone mycotoxin

RTECS

HP8757000

TSCA

not listed

Section 3. Hazards Identification

HMIS rating

Health: 4; Flamability: 0; Reactivity: 0

NFPA rating

Health: 4; Flamability: 0; Reactivity: 0

Potential health effects

 

inhalation

Potentially fatal. May irritate respiratory system

skin contact

Potentially fatal. May irritate skin.

eyes

May irritate eyes.

ingestion

Potentially fatal.

Section 4. First Aid Measures

Eye Contact

Check for and remove contact lenses. Flush eyes with running water for at least 15 minutes separating eyelids. Seek medical attention immediately.

Skin Contact

Wash with soap and water for 15 minutes. Remove contaminated clothing and shoes. Seek medical attention immediately

Inhalation

Remove from exposure. If breathing is difficult, administer oxygen. If breathing stops, administer artificial respiration. Seek medical attention immediately. Provide chemical label and MSDS if possible.

Ingestion

Remove dentures and clear mouth. If person is conscious, rinse mouth with water Call physician or poison control immediately. Provide chemical label and MSDS information if possible.

General advice

There are sources in the literature that advice giving slurry of activated carbon, 3 tablespoons in a glass of water, or more, to drink in cases of ingestion.

Section 5. Fire and Explosion Data

Flammability

Not Available

Flash Point

Not Available

Combustion Products

CO, CO2,

Extinguishing Media

Foam, Carbon Dioxide, Dry chemical powder, polymer foam, water spray

Special Firefighting Procedures

Use self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Unusual Fire/Explosion Hazards

None known

Section 6 - Accidental Release Measures

Cleanup Procedures

Evacuate area. Wear appropriate protective gear as outlined under “Protective equipment” wipe up spill and place in sealed container and hold for disposal. Avoid raising dust. Ventilate the area and wash spill site after material has been removed

Waste Disposal Method

Observe all Federal, State and Local regulations concerning the disposal of this product.

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete

Section 7 - Handling and Storage

Protective Equipment

For spill cleanup, wear suitable protective clothing, chemical resistant rubber gloves, rubber boots, and chemical safety goggles. Self contained breathing apparatus or NIOSH/MSHA approved respirator is recommended.

Storage and Handling

It should be kept in a tightly closed container. This product should be handled only by qualified experienced professionals. Wash thoroughly after handling this material. Do not store above 8oC

Section 8 - Exposure Controls / Personal protection

General

Use only in a chemical fume hood. Safety shower and eye bath. Use adequate ventilation to keep airborne concentrations low

Personal protective equipment

Respiratory: Government approved respirator.

Hand: Compatible chemical-resistant gloves.

Eye: Chemical safety goggles.

Section 9. Physical Data

Appearance

white to off-white powder

Molecular Weight

414.5

Solubility

Ethanol, Dichloromethane

Section 10. Stability and Reactivity Data

Stability

This material is stable if stored as directed

Conditions to Avoid

Excess heat, strong oxidizers

Incompatibles

Reactive with oxidizing agents, acids, alkalis.

Hazardous polymerization

Will not occur

Section 11 - Toxicological Information

RTECS#:

HP8757000

Route of exposure

Multiple Routes: May cause irritation of skin, eyes, respiratory system.
May be fatal by inhalation, ingestion, or skin absorption.

Conditions aggravated by exposure

The toxicological properties have not been thoroughly investigated.

Mutagenicitydata

Shown as mutagene in mammal cell cultures: Toxicol Lett. 2006 Jul 14;164(3):221-30 ; < >PMID: 16464542

Toxity data

Mouse LDLo intra peritoneal 100 mg/kg. Source: EHP, Environmental Health Perspectives. Vol. 4, Pg. 87, 1973.

Section 12 - Ecological Data

Ecotoxicological Information:

None Available

Section 13 - Disposal Considerations

Appropriate method of disposal of substance or preparation

Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Observe all federal, state, and local environmental regulations. Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 <> CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.

Section 14 - Transport Information

IATA

UN-Number: UN-3462 Class: 6.1 Packing group: II

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Alternariol)

US DOT

DOT (US)

UN-Number: UN-3462 Class: 6.1 Packing group: II

Proper shipping name: Toxins, extracted from living sources, solid, n.o.s. (Alternariol)

Marine pollutant: No

Poison Inhalation Hazard: No

Section 15-Regulatory Information

US classification and labeling

OSHA hazards

Highly toxic by inhalation, Highly toxic by ingestion, Highly toxic by skin absorption, Teratogen, Mutagen

USA regulatory information

SARA not listed

Canadian DSL. NDSL

Not listed

Section 16 -Other Information

Disclaimer

For R&D use only. Not for drug, household or other uses

Warranty

DISCLAIMER

For R&D use only. Not for drug, household or other uses. For use only by trained personnel. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. The burden of safe use of this material rests entirely with the user. Fermentek shall not be held liable or any damage resulting from handling or from contact with the above product.



    
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Mail Address:

Yatziv 25, Atarot industrial zone,
POB 47120, Jerusalem 97800 Israel
Fax:     972 2 5853943
Phone: 972 2 5853953